Inhibitory Effects of Columbianadin on Nociceptive Behaviors in a Neuropathic Pain Model, and on Voltage-Gated Calcium Currents in Dorsal Root Ganglion Neurons in Mice

• Egile Nagusiak: Xiaolin Su (Egilea), Bin Wu (Egilea), Wentong Zhang (Egilea), Yong-Hua Ji (Egilea), Qiuhong Wang (Egilea), Zhi-Yong Tan (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Radix angelicae pubescentis (RAP) has been used in Chinese traditional medicine to treat painful diseases such as rheumatism and headache. A previous study has reported that columbianadin (CBN), a major coumarin in RAP inhibits acute and inflammatory pain behaviors. However, the effects of CBN on ne...