Improved Tumor Control Following Radiosensitization with Ultrasound-Sensitive Oxygen Microbubbles and Tumor Mitochondrial Respiration Inhibitors in a Preclinical Model of Head and Neck Cancer

• Үндсэн зохиолчид: Quezia Lacerda (Зохиогч), Hebah Falatah (Зохиогч), Ji-Bin Liu (Зохиогч), Corinne E. Wessner (Зохиогч), Brian Oeffinger (Зохиогч), Ankit Rochani (Зохиогч), Dennis B. Leeper (Зохиогч), Flemming Forsberg (Зохиогч), Joseph M. Curry (Зохиогч), Gagan Kaushal (Зохиогч), Scott W. Keith (Зохиогч), Patrick O'Kane (Зохиогч), Margaret A. Wheatley (Зохиогч), John R. Eisenbrey (Зохиогч)
• Формат: Ном
• Хэвлэсэн: MDPI AG, 2023-04-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Tumor hypoxia (oxygen deficiency) is a major contributor to radiotherapy resistance. Ultrasound-sensitive microbubbles containing oxygen have been explored as a mechanism for overcoming tumor hypoxia locally prior to radiotherapy. Previously, our group demonstrated the ability to encapsulate and del...