Tctex-1 augments G protein-coupled receptor-mediated Gs signaling by activating adenylyl cyclase

• Main Authors: Masaki Saito (Author), Ayano Chiba (Author), Takeya Sato (Author), Takahiro Moriya (Author), Jun Sukegawa (Author), Norimichi Nakahata (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Proteins interacting with G protein-coupled receptors (GPCRs) can modulate signal transduction of these receptors. However, the regulatory mechanisms of the interacting proteins are diverse and largely unknown. We have previously shown that Tctex-1 (or DYNLT1) can interact with the parathyroid hormo...