A muscle‐specific MuRF1‐E2 network requires stabilization of MuRF1‐E2 complexes by telethonin, a newly identified substrate

• Main Authors: Cécile Polge (Author), Stéphanie Cabantous (Author), Christiane Deval (Author), Agnès Claustre (Author), Antoine Hauvette (Author), Catherine Bouchenot (Author), Julien Aniort (Author), Daniel Béchet (Author), Lydie Combaret (Author), Didier Attaix (Author), Daniel Taillandier (Author)
• Format: Book
• Published: Wiley, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Muscle wasting is observed in the course of many diseases and also during physiological conditions (disuse, ageing). Skeletal muscle mass is largely controlled by the ubiquitin‐proteasome system and thus by the ubiquitinating enzymes (E2s and E3s) that target substrates for subse...