Diosgenin ameliorates palmitic acid-induced lipid accumulation via AMPK/ACC/CPT-1A and SREBP-1c/FAS signaling pathways in LO2 cells

• Main Authors: Ke Fang (Author), Fan Wu (Author), Guang Chen (Author), Hui Dong (Author), Jingbin Li (Author), Yan Zhao (Author), Lijun Xu (Author), Xin Zou (Author), Fuer Lu (Author)
• Format: Book
• Published: BMC, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and is characterized by excessive hepatic lipid accumulation. Many studies have suggested that lipid overload is the key initial factor that contributes to hepatic steatosis. Our previous study ind...