N-Butyrylated hyaluronic acid ameliorates gout and hyperuricemia in animal models

• Main Authors: Lanzhou Li (Author), Di Wang (Author), Xueju Wang (Author), Ruifeng Bai (Author), Chunyu Wang (Author), Yin Gao (Author), Tassos Anastassiades (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context: Hyaluronic acid (HA) plays critical roles in the structural skeleton, joint lubrication, renal function and cell signaling. We previously showed that partially N-butyrylated, low molecular weight, hyaluronic acid (BHA) exhibited an anti-inflammatory effect in cultured human macrophage, wher...