N-Butyrylated hyaluronic acid ameliorates gout and hyperuricemia in animal models

• Egile Nagusiak: Lanzhou Li (Egilea), Di Wang (Egilea), Xueju Wang (Egilea), Ruifeng Bai (Egilea), Chunyu Wang (Egilea), Yin Gao (Egilea), Tassos Anastassiades (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Context: Hyaluronic acid (HA) plays critical roles in the structural skeleton, joint lubrication, renal function and cell signaling. We previously showed that partially N-butyrylated, low molecular weight, hyaluronic acid (BHA) exhibited an anti-inflammatory effect in cultured human macrophage, wher...