In Vitro Metabolism of DWP16001, a Novel Sodium-Glucose Cotransporter 2 Inhibitor, in Human and Animal Hepatocytes

• Prif Awduron: Ju-Hyun Kim (Awdur), Dong Kyun Kim (Awdur), Won-Gu Choi (Awdur), Hye-Young Ji (Awdur), Ji-Soo Choi (Awdur), Im-Sook Song (Awdur), Sangkyu Lee (Awdur), Hye Suk Lee (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2020-09-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

DWP16001 is currently in a phase 2 clinical trial as a novel anti-diabetes drug for the treatment of type 2 diabetes by selective inhibition of sodium-glucose cotransporter 2. This in vitro study was performed to compare the metabolism of DWP16001 in human, dog, monkey, mouse, and rat hepatocytes, a...