Cerebellar neuronal dysfunction accompanies early motor symptoms in spinocerebellar ataxia type 3

• 主要な著者: Kristin Mayoral-Palarz (著者), Andreia Neves-Carvalho (著者), Sara Duarte-Silva (著者), Daniela Monteiro-Fernandes (著者), Patrícia Maciel (著者), Kamran Khodakhah (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2022-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Spinocerebellar ataxia type 3 (SCA3) is an adult-onset, progressive ataxia. SCA3 presents with ataxia before any gross neuropathology. A feature of many cerebellar ataxias is aberrant cerebellar output that contributes to motor dysfunction. We examined whether abnormal cerebellar output was present...