Identification and ranking of recurrent neo-epitopes in cancer

• Main Authors: Eric Blanc (Author), Manuel Holtgrewe (Author), Arunraj Dhamodaran (Author), Clemens Messerschmidt (Author), Gerald Willimsky (Author), Thomas Blankenstein (Author), Dieter Beule (Author)
• Format: Book
• Published: BMC, 2019-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Immune escape is one of the hallmarks of cancer and several new treatment approaches attempt to modulate and restore the immune system's capability to target cancer cells. At the heart of the immune recognition process lies antigen presentation from somatic mutations. These...