4-O-Carboxymethylascochlorin Inhibits Expression Levels of on Inflammation-Related Cytokines and Matrix Metalloproteinase-9 Through NF-κB/MAPK/TLR4 Signaling Pathway in LPS-Activated RAW264.7 Cells

• Main Authors: Junyoung Park (Author), Sun-Hyung Ha (Author), Fukushi Abekura (Author), Hakseong Lim (Author), Juni Magae (Author), Ki-Tae Ha (Author), Tae-Wook Chung (Author), Young-Chae Chang (Author), Young-Choon Lee (Author), Eunyong Chung (Author), Jiyeon Ku (Author), Cheorl-Ho Kim (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Toll-like receptor 4 (TLR4) and matrix metalloproteinase-9 (MMP-9) are known to play important roles in inflammatory diseases such as arteriosclerosis and plaque instability. The purpose of this study was to perform the effect of 4-O-carboxymethylascochlorin (AS-6) on MMP-9 expression in lipopolysac...