Targeting allosteric sites of human aromatase: a comprehensive in-silico and in-vitro workflow to find potential plant-based anti-breast cancer therapeutics
Recent findings suggested several allosteric pockets on human aromatase that could be utilised for the development of new modulators able to inhibit this enzyme in a new mechanism. Herein, we applied an integrated in-silico-based approach supported by in-vitro enzyme-based and cell-based validation...
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Main Authors: | Hani A. Alhadrami (Author), Ahmed M. Sayed (Author), Sami A. Melebari (Author), Asem A. Khogeer (Author), Wesam H. Abdulaal (Author), Mohamed B. Al-Fageeh (Author), Mohammad Algahtani (Author), Mostafa E. Rateb (Author) |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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