Impact of particle size and pH on protein corona formation of solid lipid nanoparticles: A proof-of-concept study

• Main Authors: Wenhao Wang (Author), Zhengwei Huang (Author), Yanbei Li (Author), Wenhua Wang (Author), Jiayu Shi (Author), Fangqin Fu (Author), Ying Huang (Author), Xin Pan (Author), Chuanbin Wu (Author)
• Format: Book
• Published: Elsevier, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

When nanoparticles were introduced into the biological media, the protein corona would be formed, which endowed the nanoparticles with new bio-identities. Thus, controlling protein corona formation is critical to in vivo therapeutic effect. Controlling the particle size is the most feasible method d...