Nicorandil Improves Glomerular Injury in Rats With Mesangioproliferative Glomerulonephritis via Inhibition of Proproliferative and Profibrotic Growth Factors

• Main Authors: Hirokazu Sudo (Author), Michinori Hirata (Author), Hirotaka Kanada (Author), Keigo Yorozu (Author), Yoshihito Tashiro (Author), Ken-ichi Serizawa (Author), Kenji Yogo (Author), Motoyuki Kataoka (Author), Yoshiyuki Moriguchi (Author), Nobuhiko Ishizuka (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent clinical studies on chronic kidney disease (CKD) reported that renal dysfunction was a critical risk factor for cardiovascular events (CVE), which lead us to reconsider the effect of cardioprotective agents on the kidney. Glomerulonephritis, which is the major cause of CKD, is characterized b...