Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy

• Main Authors: Giuseppe Labruna (Author), Fabrizio Pasanisi (Author), Giuliana Fortunato (Author), Carmela Nardelli (Author), Carmine Finelli (Author), Eduardo Farinaro (Author), Franco Contaldo (Author), Lucia Sacchetti (Author)
• Format: Book
• Published: Hindawi Limited, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Brown adipose tissue, where Uncoupling Protein 1 (UCP1) activity uncouples mitochondrial respiration, is an important site of facultative energy expenditure. This tissue may normally function to prevent obesity. Our aim was to investigate by sequence analysis the presence of UCP1 gene variations tha...