Effects of Dimerization, Dendrimerization, and Chirality in p-BthTX-I Peptide Analogs on the Antibacterial Activity and Enzymatic Inhibition of the SARS-CoV-2 PL^pro Protein

• Main Authors: Natália Vitória Bitencourt (Author), Gabriela Marinho Righetto (Author), Ilana Lopes Baratella Cunha Camargo (Author), Mariana Ortiz de Godoy (Author), Rafael Victorio Carvalho Guido (Author), Glaucius Oliva (Author), Norival Alves Santos-Filho (Author), Eduardo Maffud Cilli (Author)
• Format: Book
• Published: MDPI AG, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies have shown that the peptide [des-Cys¹¹,Lys¹²,Lys¹³-(p-BthTX-I)₂K] (p-Bth) is a p-BthTX-I analog that shows enhanced antimicrobial activity, stability and hemolytic activity, and is easy to obta...