Hyaluronic Acid Coating Reduces the Leakage of Melittin Encapsulated in Liposomes and Increases Targeted Delivery to Melanoma Cells

Melittin is a promising antitumor substance; however, it is a nonspecific cytolytic peptide, which limits its clinical application. In this study, melittin liposomes (Mel-Lip) and hyaluronic acid (HA)-modified Mel-Lip (Mel-HA-Lip) were designed to reduce the toxicity and increase the anti-tumor effe...

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Main Authors: Yanyan Li (Author), Shuyao Ruan (Author), Zhi Wang (Author), Nianping Feng (Author), Yongtai Zhang (Author)
Format: Book
Published: MDPI AG, 2021-08-01T00:00:00Z.
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