Using simulation to aid trial design: Ring-vaccination trials.
BACKGROUND:The 2014-6 West African Ebola epidemic highlights the need for rigorous, rapid clinical trial methods for vaccines. A challenge for trial design is making sample size calculations based on incidence within the trial, total vaccine effect, and intracluster correlation, when these parameter...
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| Format: | Book |
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Public Library of Science (PLoS),
2017-03-01T00:00:00Z.
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