15d-Prostaglandin J2 Enhancement of Nerve Growth Factor-Induced Neurite Outgrowth Is Blocked by the Chemoattractant Receptor- Homologous Molecule Expressed on T-Helper Type 2 Cells (CRTH2) Antagonist CAY10471 in PC12 Cells

• Hlavní autoři: Michiyoshi Hatanaka (Autor), Norihiro Shibata (Autor), Norihito Shintani (Autor), Ryota Haba (Autor), Atsuko Hayata (Autor), Hitoshi Hashimoto (Autor), Akemichi Baba (Autor)
• Médium: Kniha
• Vydáno: Elsevier, 2010-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

The chemoattractant receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) is the most recently identified prostaglandin (PG) receptor for both PGD2 and 15-deoxy-Δ12,14-PGJ2 (15d-PGJ2). We examined the mechanism by which 15d-PGJ2 enhances nerve growth factor (NGF)-induced neurite ou...