QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology

• Main Authors: Meng Li (Author), Yueyao Wang (Author), Zhongwen Qi (Author), Zhuo Yuan (Author), Shichao Lv (Author), Yawei Zheng (Author), Zhipeng Yan (Author), Mingyang Wang (Author), Huanjie Fu (Author), Xinbiao Fan (Author), Nan Ji (Author), Ming Liu (Author), Zhuyuan Fang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Myocardial ischemia/reperfusion (I/R) injury is associated with multiple serious clinical manifestations. Autophagy is upregulated in a short period of ischemia and further enhanced during reperfusion phase, which was considered as a "double-edged sword" in the pathological pro...