Endothelial Effects of Simultaneous Expression of Human HO-1, E5NT, and ENTPD1 in a Mouse

• Main Authors: Paulina Mierzejewska (Author), Noemi Di Marzo (Author), Magdalena A. Zabielska-Kaczorowska (Author), Iga Walczak (Author), Ewa M. Slominska (Author), Marialuisa Lavitrano (Author), Roberto Giovannoni (Author), Barbara Kutryb-Zajac (Author), Ryszard T. Smolenski (Author)
• Format: Book
• Published: MDPI AG, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The vascular endothelium is key target for immune and thrombotic responses that has to be controlled in successful xenotransplantation. Several genes were identified that, if induced or overexpressed, help to regulate the inflammatory response and preserve the transplanted organ function and metabol...