In Silico Activity Prediction and Docking Studies of the Binding Mechanisms of Levofloxacin Structure Derivatives to Active Receptor Sites of Bacterial Type IIA Topoisomerases

• Main Authors: Elena V. Uspenskaya (Author), Vasilisa A. Sukhanova (Author), Ekaterina S. Kuzmina (Author), Tatyana V. Pleteneva (Author), Olga V. Levitskaya (Author), Timur M. Garaev (Author), Anton V. Syroeshkin (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

The need for new antimicrobial agents (AntAg) is driven by the persistent antibiotic resistance in microorganisms, as well as the increasing frequency of pandemics. Due to the deficiency of AntAg, research aimed at developing speedy approaches to find new drug candidates is relevant. This study aims...