Determination of cefcapene acid by LCâMS and their application to a pharmacokinetic study in healthy Chinese volunteers

• Main Authors: Hong-Fei Duan (Author), Li Ding (Author), Xiao-Bing Li (Author), Lin-Lin Hu (Author), Ai-Dong Wen (Author), Ye Leng (Author), Zhen Liu (Author)
• Format: Book
• Published: Elsevier, 2013-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Simple, rapid and specific liquid chromatographyâmass spectrometry (LCâMS) methods have been developed and validated for the quantification of cefcapene acid in human plasma and urine. Plasma samples were simply pretreated with methanol for deproteinization. Urine samples were briefly diluted with m...