Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanoma

• Main Authors: Qiong Chen (Author), Yang Liu (Author), Yunxuan Zhu (Author), Ziyan Zhu (Author), Jueyao Zou (Author), Yanhong Pan (Author), Yin Lu (Author), Wenxing Chen (Author)
• Format: Book
• Published: BMC, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cutaneous melanoma is a kind of skin malignancy with low morbidity but high mortality. Cryptotanshinone (CPT), an important component of salvia miltiorrhiza has potent anti-tumor activity and also indicates therapeutic effect on dermatosis. So we thought that CPT maybe a potentia...