Enhancement of norfloxacin solubility via inclusion complexation with β-cyclodextrin and its derivative hydroxypropyl-β-cyclodextrin

The objectives of the study were to investigate the effects of β-cyclodextrin (βCD) and hydroxypropyl-β-cyclodextrin (HPβCD) on the solubility and dissolution rate of norfloxacin prepared using three different methods, at drug to cyclodextrin weight ratios of 1:1, 1:2, 1:4 and 1:8. All the methods i...

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Main Authors: Gabriel Onn Kit Loh (Author), Yvonne Tze Fung Tan (Author), Kok-Khiang Peh (Author)
Format: Book
Published: Elsevier, 2016-08-01T00:00:00Z.
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