HVEM/HIF-1α promoted proliferation and inhibited apoptosis of ovarian cancer cells under hypoxic microenvironment conditions

• Main Authors: Liyan Duan (Author), Jie Tao (Author), Xiaoqian Yang (Author), Lei Ye (Author), Yueqian Wu (Author), Qizhi He (Author), Yingchun Duan (Author), Li Chen (Author), Jianlong Zhu (Author)
• Format: Book
• Published: BMC, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Our previous studies showed the expression of herpes virus entry mediator (HVEM) is high in ovarian cancer samples and correlated to the patient clinic pathological features. As we all know, the hypoxic environment is the main feature of tumor. In this work, we explored the role...