Challenges with sirolimus experimental data to inform QSP model of post‐transplantation cyclophosphamide regimens

• Asıl Yazarlar: Ezhilpavai Mohanan (Yazar), Guofang Shen (Yazar), Suping Ren (Yazar), Hsuan‐Hao Fan (Yazar), Kao Tang Ying Moua (Yazar), Aleksandra Karolak (Yazar), Russell C. Rockne (Yazar), Ryotaro Nakamura (Yazar), David A. Horne (Yazar), Christopher G. Kanakry (Yazar), Donald E. Mager (Yazar), Jeannine S. McCune (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2024-08-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Dose optimization of sirolimus may further improve outcomes in allogeneic hematopoietic cell transplant (HCT) patients receiving post‐transplantation cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD). Sirolimus exposure-response association studies in HCT patients (i.e., t...