Probing the Druggablility on the Interface of the Protein-Protein Interaction and Its Allosteric Regulation Mechanism on the Drug Screening for the CXCR4 Homodimer

Modulating protein-protein interactions (PPIs) with small drug-like molecules targeting it exhibits great promise in modern drug discovery. G protein-coupled receptors (GPCRs) are the largest family of targeted proteins and could form dimers in living biological cells through PPIs. However, compared...

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Main Authors: Liting Shen (Author), Yuan Yuan (Author), Yanzhi Guo (Author), Menglong Li (Author), Chuan Li (Author), Xuemei Pu (Author)
Format: Book
Published: Frontiers Media S.A., 2019-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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