Valproic acid induces histologic changes and decreases androgen receptor levels of testis and epididymis in rats

• Main Authors: Sitthichai Iamsaard (Author), Wannisa Sukhorum (Author), SupatchareeArun (Author), Nichapa Phunchago (Author), Nongnuch Uabundit (Author), Porntip Boonruangsri (Author), Malivalaya Namking (Author)
• Format: Book
• Published: Shahid Sadoughi University of Medical Sciences, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Valproic acid (VPA), an anti-epileptic drug, can cause male subfertility. However, the degree to which testicular and epididymal histopathologies and androgen receptor (AR) expression are changed under VPA treatment has never been reported. Objective: To investigate the histopathological...