Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells

• Glavni autori: Lu-Kai Wang (Autor), Tsai-Jung Wu (Autor), Ji-Hong Hong (Autor), Fang-Hsin Chen (Autor), John Yu (Autor), Chun-Chieh Wang (Autor)
• Format: Knjiga
• Izdano: Hindawi Limited, 2020-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

The lung is a radiosensitive organ, which imposes limits on the therapeutic dose in thoracic radiotherapy. Irradiated alveolar epithelial cells promote radiation-related pneumonitis and fibrosis. However, the role of lung stem cells (LSCs) in the development of radiation-induced lung injury is still...