PLGA-PEG-ANG-2 Nanoparticles for Blood-Brain Barrier Crossing: Proof-of-Concept Study

• Main Authors: Gina P. Hoyos-Ceballos (Author), Barbara Ruozi (Author), Ilaria Ottonelli (Author), Federica Da Ros (Author), Maria Angela Vandelli (Author), Flavio Forni (Author), Eleonora Daini (Author), Antonietta Vilella (Author), Michele Zoli (Author), Giovanni Tosi (Author), Jason T. Duskey (Author), Betty L. López-Osorio (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The treatment of diseases that affect the central nervous system (CNS) represents a great research challenge due to the restriction imposed by the blood−brain barrier (BBB) to allow the passage of drugs into the brain. However, the use of modified nanomedicines engineered with different ligands that...