The Real Cytotoxic Effect of Artemisinins on Colon Cancer Cells in a Physiological Cell Culture Setting. How Composition of the Culture Medium Biases Experimental Findings

• Main Authors: Dagmara Otto-Ślusarczyk (Author), Magdalena Mielczarek-Puta (Author), Wojciech Graboń (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2021-09-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Artemisinin (ART) and dihydroartemisinin (DHA) are anti-malaria drugs but also exhibit huge anticancer potential based on ferroptosis driven by iron-dependent lipid peroxidation. This study was conducted on primary (SW480), metastatic (SW620) colon cancer, and noncancerous HaCaT cells at pharmacolog...