Effects of clozapine on adipokine secretions/productions and lipid droplets in 3T3-L1 adipocytes

• Main Authors: Tomomi Tsubai (Author), Akira Yoshimi (Author), Yoji Hamada (Author), Makoto Nakao (Author), Hiroshi Arima (Author), Yutaka Oiso (Author), Yukihiro Noda (Author)
• Format: Book
• Published: Elsevier, 2017-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clozapine, a second-generation antipsychotic (SGA), is a cause of side effects related to metabolic syndrome. The participation of serotonin 5-HT2C and histamine H1 receptors in the central nervous system has been reported as a mechanism of the weight gain caused by clozapine. In the present study,...