Juvenile idiopathic arthritis with systemic onset with inflammatory bone lesions: two case reports of patients successfully treated with canakinumab and experience gained from literature

• Main Authors: Ekaterina I. Alexeeva (Author), Tatyana M. Dvoryakovskaya (Author), Irina T. Tsulukiya (Author), Natalia M. Kondrateva (Author), Natalia M. Solomatina (Author), Gleb V. Kondratiev (Author), Luliia V. Peshekhonova (Author), Mikhail M. Kostik (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-bacterial osteomyelitis (NBO) is a rare chronic inflammatory bone disease related to immune system dysregulation. This disease belongs to a family of autoinflammatory diseases. It often coexists with other TNF-α-mediated immune-mediated diseases such as juvenile idiopathic arthritis (JIA) and in...