Fat tissue regulates the pathogenesis and severity of cardiomyopathy in murine chagas disease.

• Main Authors: Kezia Lizardo (Author), Janeesh P Ayyappan (Author), Neelam Oswal (Author), Louis M Weiss (Author), Philipp E Scherer (Author), Jyothi F Nagajyothi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic Chagas cardiomyopathy (CCC) caused by a parasite Trypanosoma cruzi is a life-threatening disease in Latin America, for which there is no effective drug or vaccine. The pathogenesis of CCC is complex and multifactorial. Previously, we demonstrated T. cruzi infected mice lose a significant amo...