The Nonsteroidal Anti-Inflammatory Drug Ketorolac Alters the Small Intestinal Microbiota and Bile Acids Without Inducing Intestinal Damage or Delaying Peristalsis in the Rat

• Main Authors: Barbara Hutka (Author), Bernadette Lázár (Author), András S. Tóth (Author), Bence Ágg (Author), Szilvia B. László (Author), Nóra Makra (Author), Balázs Ligeti (Author), Bálint Scheich (Author), Kornél Király (Author), Mahmoud Al-Khrasani (Author), Dóra Szabó (Author), Péter Ferdinandy (Author), Klára Gyires (Author), Zoltán S. Zádori (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) induce significant damage to the small intestine, which is accompanied by changes in intestinal bacteria (dysbiosis) and bile acids. However, it is still a question of debate whether besides mucosal inflammation also other factors, such as di...