Philadelphia chromosome positive AML arising from JAK2-positive myelofibrosis

• Autori principali: Marte Karen Brattås (Autore), Kyrre Lilleeng (Autore), Randi Hovland (Autore), Ingvild Jenssen Lægreid (Autore), Marta Vorland (Autore), Friedemann Leh (Autore), Øystein Bruserud (Autore), Bjørn Tore Gjertsen (Autore), Håkon Reikvam (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2018-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background A feature of myeloproliferative neoplasia is transforming to more aggressive and malignant myeloid neoplasia, including acute myeloid leukemia. Different pathogenesis mechanisms participate in transformation, including transformation of existing potential preleukemic clones, sinc...