Caffeine for the Pharmacological Treatment of Apnea of Prematurity in the NICU: Dose Selection Conundrum, Therapeutic Drug Monitoring and Genetic Factors

• Main Authors: Jia-Yi Long (Author), Hong-Li Guo (Author), Xin He (Author), Ya-Hui Hu (Author), Ying Xia (Author), Rui Cheng (Author), Xuan-Sheng Ding (Author), Feng Chen (Author), Jing Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Caffeine citrate is the drug of choice for the pharmacological treatment of apnea of prematurity. Factors such as maturity and genetic variation contribute to the interindividual variability in the clinical response to caffeine therapy in preterm infants, making the optimal dose administered controv...