Immunogenicity of a protective intradermal DNA vaccine against lassa virus in cynomolgus macaques

• Main Authors: Jingjing Jiang (Author), Preeti Banglore (Author), Kathleen A. Cashman (Author), Connie S. Schmaljohn (Author), Katherine Schultheis (Author), Holly Pugh (Author), Jacklyn Nguyen (Author), Laurent M. Humeau (Author), Kate E. Broderick (Author), Stephanie J. Ramos (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lassa virus (LASV) is a hemorrhagic fever virus of the Arenaviridae family with high rates of mortality and co-morbidities, including chronic seizures and permanent bilateral or unilateral deafness. LASV is endemic in West Africa and Lassa fever accounts for 10-16% of hospitalizations annually in pa...