BNTA alleviates inflammatory osteolysis by the SOD mediated anti-oxidation and anti-inflammation effect on inhibiting osteoclastogenesis

• Main Authors: Huidong Wang (Author), Xiankun Cao (Author), Jiadong Guo (Author), Xiao Yang (Author), Xiaojiang Sun (Author), Zhiyi Fu (Author), An Qin (Author), Yujie Wu (Author), Jie Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abnormal activation and overproliferation of osteoclast in inflammatory bone diseases lead to osteolysis and bone mass loss. Although current pharmacological treatments have made extensive advances, limitations still exist. N-[2-bromo-4-(phenylsulfonyl)-3-thienyl]-2-chlorobenzamide (BNTA) is an arti...