Epigallocatechin-3-Gallate Suppresses BMP-6-Mediated SMAD1/5/8 Transactivation of Hepcidin Gene by Inducing SMILE in Hepatocytes

Hepcidin, a major regulator of systemic iron homeostasis, is mainly induced in hepatocytes by activating bone morphogenetic protein 6 (BMP-6) signaling in response to changes in the iron status. Small heterodimer partner-interacting leucine zipper protein (SMILE), a polyphenol-inducible transcriptio...

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Main Authors: Yu-Ji Kim (Author), Woo-Ram Park (Author), Byungyoon Choi (Author), Hueng-Sik Choi (Author), Don-Kyu Kim (Author)
Format: Book
Published: MDPI AG, 2021-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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