Inhibition of Receptor-Interacting Protein Kinase 1 in Chronic Plaque Psoriasis: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study

• Main Authors: Valerie J. Ludbrook (Author), David C. Budd (Author), Katie Thorn (Author), Debra Tompson (Author), Bartholomew J. Votta (Author), Lucy Walker (Author), Amy Lee (Author), Xin Chen (Author), Amanda Peppercorn (Author), Wei Jing Loo (Author)
• Format: Book
• Published: Adis, Springer Healthcare, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Introduction Receptor-interacting protein kinase 1 (RIPK1), a key mediator of inflammation through necroptosis and proinflammatory cytokine production, may play a role in the pathogenesis of immune-mediated inflammatory diseases such as chronic plaque psoriasis. An experimental medicine stu...