Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders

Alum adjuvant is more effective than MF59 at prompting early germinal center formation in response to peptide-protein conjugates and enhancing efficacy of a vaccine against opioid use disorders

Opioid use disorders (OUD) and fatal overdoses are a national emergency in the United States. Therapeutic vaccines offer a promising strategy to treat OUD and reduce the incidence of overdose. Immunization with opioid-based haptens conjugated to immunogenic carriers elicits opioid-specific antibodie...

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Main Authors: Christine Robinson (Author), Carly Baehr (Author), Shirdi E. Schmiel (Author), Claudia Accetturo (Author), Daniel L. Mueller (Author), Marco Pravetoni (Author)
Format: Book
Published: Taylor & Francis Group, 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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