Peripheral Circulation and Astrocytes Contribute to the MSC-Mediated Increase in IGF-1 Levels in the Infarct Cortex in a dMCAO Rat Model

• Autors principals: Xiaobo Li (Autor), Wenxiu Yu (Autor), Yunqian Guan (Autor), Haiqiang Zou (Autor), Zhaohui Liang (Autor), Min Huang (Autor), Renchao Zhao (Autor), Chunsong Zhao (Autor), Zhenhua Ren (Autor), Zhiguo Chen (Autor)
• Format: Llibre
• Publicat: Hindawi Limited, 2020-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Background and Purpose. Previously, we found that insulin-like growth factor-1 (IGF-1) levels in the infarct cortex in the acute phase of distal middle cerebral artery occlusion (dMCAO) rats are increased by intravenous infusion of allogeneic mesenchymal stem/stromal cells (MSCs). CD68+ microglia an...