Genetic Risk Score Increased Discriminant Efficiency of Predictive Models for Type 2 Diabetes Mellitus Using Machine Learning: Cohort Study

• Main Authors: Yikang Wang (Author), Liying Zhang (Author), Miaomiao Niu (Author), Ruiying Li (Author), Runqi Tu (Author), Xiaotian Liu (Author), Jian Hou (Author), Zhenxing Mao (Author), Zhenfei Wang (Author), Chongjian Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Previous studies have constructed prediction models for type 2 diabetes mellitus (T2DM), but machine learning was rarely used and few focused on genetic prediction. This study aimed to establish an effective T2DM prediction tool and to further explore the potential of genetic risk scores...