Interleukin 35 Polymorphisms Are Associated with Decreased Risk of Premature Coronary Artery Disease, Metabolic Parameters, and IL-35 Levels: The Genetics of Atherosclerotic Disease (GEA) Study

• Main Authors: Rosalinda Posadas-Sánchez (Author), Nonanzit Pérez-Hernández (Author), Javier Angeles-Martínez (Author), Fabiola López-Bautista (Author), Teresa Villarreal-Molina (Author), José Manuel Rodríguez-Pérez (Author), José Manuel Fragoso (Author), Carlos Posadas-Romero (Author), Gilberto Vargas-Alarcón (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Interleukin 35 (IL-35) is a heterodimeric cytokine involved in the development of atherosclerosis. The aim of the present study was to establish if the polymorphisms of IL-12A and EBI3 genes that encode the IL-35 subunits are associated with the development of premature coronary artery disease (CAD)...