Mast Cell Tryptase Stimulates DLD-1 Carcinoma Through Prostaglandin- and MAP Kinase-Dependent Manners

• Main Authors: Masanori Yoshii (Author), Atsushi Jikuhara (Author), Shuji Mori (Author), Hiromi Iwagaki (Author), Hideo K. Takahashi (Author), Masahiro Nishibori (Author), Noriaki Tanaka (Author)
• Format: Book
• Published: Elsevier, 2005-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We found that striptease-positive mast cells were abundant in the invasive front of human colon adenocarcinoma by examining 30 cases. Because tryptase has been suggested to be the agonist proteinase for protease-activated receptor-2 (PAR-2), we investigated the effects of stimulation of PAR-2 by try...