Insights from lncRNAs Profiling of MIN6 Beta Cells Undergoing Inflammation

• Main Authors: Chuntao Sun (Author), Lihua Xue (Author), Ziyang Zhu (Author), Fan Zhang (Author), Ruixue Yang (Author), Xuewen Yuan (Author), Zhanjun Jia (Author), Qianqi Liu (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type 1 diabetes mellitus (T1DM) is an organ-specific autoimmune disease characterized by chronic and progressive apoptotic destruction of pancreatic beta cells. During the initial phases of T1DM, cytokines and other inflammatory mediators released by immune cells progressively infiltrate islet cells...