Radioactive I Seed Inhibits Cell Migration and Invasion and Promotes Apoptosis by Inactivating the VEGFR2 Signaling Pathway in Cholangiocarcinoma

• Main Authors: Jun Luo (Author), Jiaping Zheng (Author), Hongxiang Yao (Author), Binbing Wang (Author), Zhewei Zhang (Author), Guoliang Shao (Author)
• Format: Book
• Published: SAGE Publishing, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives To investigate the potential mechanisms of 125 I seed implantation therapeutic treatment on inactivating the VEGFR2/PI3K/AKT pathway in cholangiocarcinoma. Methods The human cholangiocarcinoma cell lines HCCC-9810 and HuCCT1 were purchased for in vitro studies. The BALB/c nude mice were o...