Cross-reactive neutralizing antibody responses to enterovirus 71 infections in young children: implications for vaccine development.

• Main Authors: Mei-Liang Huang (Author), Pai-Shan Chiang (Author), Min-Yuan Chia (Author), Shu-Ting Luo (Author), Luan-Yin Chang (Author), Tzou-Yien Lin (Author), Mei-Shang Ho (Author), Min-Shi Lee (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Recently, enterovirus 71 (EV71) has caused life-threatening outbreaks involving neurological and cardiopulmonary complications in Asian children with unknown mechanism. EV71 has one single serotype but can be phylogenetically classified into 3 main genogroups (A, B and C) and 11 genotype...