Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases

• Main Authors: Tomohisa Ogawa (Author), Yu Tobishima (Author), Shizuka Kamata (Author), Youhei Matsuda (Author), Koji Muramoto (Author), Masafumi Hidaka (Author), Eugene Futai (Author), Takeshi Kuraishi (Author), Shinichi Yokota (Author), Motonori Ohno (Author), Shosaku Hattori (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Snakebites are one of the major causes of death and long-term disability in the developing countries due to the presence of various bioactive peptides and proteins in snake venom. In Japan, the venom of the habu snake (Protobothrops flavoviridis) causes severe permanent damage due to its myonecrotic...